High respiratory rate

NEWS calls

A rising respiratory rate is often the earliest sign of deterioration — count it over a full minute.

Anxiety is a diagnosis of exclusion.

Act now

  1. 1

    Sit up; oxygen to target (94–98%, or 88–92% if at risk of hypercapnia).

  2. 2

    Calculate NEWS2. Suspected sepsis: follow the sepsis pathway.

Assess

  • ABCDE: SpO₂, work of breathing, chest sounds, heart rate, BP, temperature, GCS.
  • Lungs: pneumonia, asthma or COPD, pleural effusion, pneumothorax.
  • Heart and vessels: pulmonary oedema, PE, arrhythmia.
  • Metabolic acidosis (deep, sighing breaths): sepsis, DKA, AKI, salicylate or toxic alcohol.
  • Pain, fever, anaemia.

Investigations

  • Blood gas: pH, CO₂, lactate, glucose; ketones if diabetic.
  • CXR, ECG, FBC, U&E, CRP; Wells score and D-dimer or CTPA if PE is possible.

Manage

  • Treat the cause: antibiotics for pneumonia, diuretic for pulmonary oedema, bronchodilators for asthma or COPD, anticoagulation for PE, analgesia for pain.
  • Reassess the respiratory rate after each intervention.

Escalate when

  • RR 25 or more, rising oxygen need, a rising CO₂ or acidosis, or the patient tiring: senior, outreach and critical care.

Written to current guidance (NICE NG253, NG158, NG250) · sources checked 14 Nov 2026. We watch NICE for updates weekly.

Sources (5)

Reviewed by Aboodee Alhasso, MPharm MRCPharm IP on 14 Nov 2026

Calculators for this

For healthcare professionals, as an aid to clinical judgement — not a substitute for it. Follow your local policy and ask a senior when in doubt.